"Anything would be possible at any moment, and the region will get out of control," Iranian Foreign Minister Hossein Amirabdollahian said during a briefing in Tehran on Sunday.
Iran has repeated over recent days that its regional allies, mainly the Lebanese militant group Hezbollah, might lose their patience and engage in a conflict with Israel.
Amirabdollahian spoke on Sunday after meeting with his South African counterpart, Naledi Pandor.
Meanwhile, Israeli warplanes struck targets across Gaza overnight and into Sunday, as well as two airports in Syria and a mosque in the occupied West Bank allegedly used by militants, as the two-week-old war with Hamas threatened to spiral into a broader conflict.
Israel has traded fire with Hezbollah on a near-daily basis since the war began, and tensions are soaring in the Israeli-occupied West Bank, where Israeli forces have battled militants in refugee camps and carried out two airstrikes in recent days.