Malawi received the initial shipment of tests, kicking off a global diagnostics programme aimed to speed up the detection of outbreaks.
In total, more than 1.2 million tests will be distributed to 14 high-risk countries over coming months, the UN health agency said in a statement.
"Countries that will receive kits in the coming weeks in this largest-ever global deployment include those currently severely impacted by cholera outbreaks, such as Ethiopia, Somalia, Syria, and Zambia," the statement said.
The program is a joint venture, with the Gavi vaccine alliance handling funding and coordination and the UN children's agency UNICEF taking care of procurement.
WHO said that it and the Global Task Force on Cholera Control were also lending their support.
The program is aimed at helping countries speed up and improve the accuracy of cholera outbreak detection and response by boosting routine surveillance and testing capacity, the organizations said.
"We are experiencing an unprecedented multi-year upsurge in cholera cases worldwide, and today's announcement provides a critical boost in the fight against the disease," Gavi's chief program officer Aurelia Nguyen said in the statement.
Cholera, which is contracted from a bacterium generally transmitted through contaminated food or water, causes diarrhea and vomiting, and can be especially dangerous for young children.
Cases have been surging in recent years, with 473,000 globally reported to WHO in 2022 — double the previous year — and preliminary data indicating that more than 700,000 cases were reported last year.
The soaring number of outbreaks has created unprecedented demand for vaccines from impacted countries.
Even though the global supply of oral cholera vaccines ballooned eighteen-fold between 2013 and 2023, the surging demand has created a global shortage, Friday's statement said.
WHO last month called for "immediate action" to address the shortage, warning of "unprecedented pressure on the global stockpile of vaccines."
The situation, it said Friday, has forced delays in preventative vaccination campaigns to preserve doses for emergency outbreak responses.
At the same time, recurring outbreaks in countries where emergency vaccination campaigns have already been carried out, shows a clear need to improve the speed and accuracy in identifying areas where new or persistent transmission is occurring, the statement said.
"Surveillance diagnostics help pinpoint hotspots with great precision," Leila Pakkala, head of UNICEF's supply division, said in the statement.
"This allows partners to target cholera vaccines to exactly the time and place where the limited supply will save the most lives."
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