The Ukrainian air force also said Russia had launched 35 S-300 missiles, which Ukraine's air defences are unable to shoot down, at the Kharkiv and Zaporizhizhia regions.
At least 17 missiles hit the southeastern city of Zaporizhzhia in an hour, acting mayor Anatolii Kurtiev said, and the state grid operator said high-voltage facilities across the country had been hit and electricity supplies shut down.
"Energy and industrial infrastructure" suffered damaged in Zaporizhzhia, local official Anatoly Kurtev said.
Critical infrastructure was also hit in Khmelnitskyi in the west and the Dnipropetrovsk region in central Ukraine, regional officials said.
Ukraine's energy operator Ukrenergo, said "several high voltage facilities" were affected in the eastern, western and southern regions of Ukraine, leading to power outages in some areas.
Russia also targeted "power plants and transmission system facilities," Ukrenergo said, adding that emergency power cuts have been put into place.
Air force spokesperson Yuriy Ihnat told Ukrainian television that Ukrainian air defenses had shot down five of seven drones and five out of six Kaliber missiles.
Russia has repeatedly struck civilian infrastructure far from the front lines over the last four months, leaving millions of Ukrainians in major cities without power, heat or water for days at a time in the middle of winter.
Ukraine has been bracing itself for a new Russian offensive in the belief that, after months of reverses, President Vladimir Putin wants to be able to tout a battlefield success before the anniversary of the invasion he launched on Feb. 24.
This report was compiled from Reuters and Agence France-Presse.
