The Gaza health ministry said another 50 people were wounded in the strike next to a hospital in the Tel Al-Sultan area of Rafah. One of the dead was a medic at the hospital. The Israeli military did not immediately respond to a request for comment.
"The strike hit one tent, where people took shelter, directly, shrapnel came inside the hospital where me and friends were sitting, we survived by a miracle," a witness told Reuters by phone from the area, declining to be identified.
The Israeli military said its forces killed eight militants in Khan Younis, around 20 militants in the central Gaza Strip and three more in Rimal, near Gaza City.
The hostilities came amid uncertainty over whether negotiations on a Gaza cease-fire would resume on Sunday.
Well over a million Palestinians have been seeking refuge in the Rafah area — in the south of Gaza — fleeing the Israeli offensive which has laid waste to much of the Gaza Strip, killing more than 30,000 people, according to health authorities in Hamas-run Gaza.
Israel launched the offensive in response to the October 7 attack by the Palestinian militant group, in which 1,200 people were killed in Israel and another 253 abducted, according to Israeli tallies.
U.S. President Joe Biden has said he hopes a cease-fire will be in place by the time of the Muslim fasting month of Ramadan, which starts on March 10. Speaking to reporters on Friday, he said: "We’re not there yet."
International pressure for a cease-fire has grown, with the United Nations warning that a quarter of the population of 2.3 million people are one step away from famine in the territory blockaded by Israel.
Three people searching for food in farmland in the northern Gaza Strip area of Beit Hanoun on Saturday were killed by Israeli strikes, residents and medics said. The Israeli military did not immediately respond to a request for comment.
Thirteen children have died at the Kamal Adwan hospital in northern Gaza in the last three days from dehydration and malnutrition, according to the Gaza Ministry of Health.
Doctors at the hospital said more were at risk of dying. "When a child is supposed to eat three meals a day and he only eats one, he obviously suffers from malnutrition, and all the diseases that come because of it," said Doctor Imad Dardonah.
On Friday, Biden announced plans to carry out a first military airdrop of food and supplies into Gaza, a day after the deaths of Palestinians queuing for aid drew renewed attention to the humanitarian catastrophe.
Health authorities in Gaza said 115 people were killed in Thursday's incident, attributing the deaths to Israeli fire and calling it a massacre.
Israel disputed those figures and said most victims were trampled or run over.
Cease-fire talks
Israel and Hamas have been negotiating via mediators including Egypt and Qatar.
Two Egyptian security sources said Israeli and Hamas delegations were expected to arrive in Cairo on Sunday to resume indirect talks.
But an Israeli report cast doubt on this.
There was no immediate comment from Israel or Hamas.
The Egyptian sources said the parties had agreed on the duration of a Gaza truce, as well as hostage and prisoner releases, adding that the completion of the deal still requires an agreement on the withdrawal of Israeli forces from northern Gaza and a return of its residents.
However, Israel's Ynet news, citing an unnamed senior official, reported that Israel would not be sending a delegation to the Cairo talks until it received a full list of hostages held in Gaza who were alive.
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